# Copyright 2013-2024 Lawrence Livermore National Security, LLC and other
# Spack Project Developers. See the top-level COPYRIGHT file for details.
#
# SPDX-License-Identifier: (Apache-2.0 OR MIT)

from spack.package import *


class PyMisopy(PythonPackage):
    """MISO (Mixture of Isoforms) is a probabilistic framework that
    quantitates the expression level of alternatively spliced genes from
    RNA-Seq data, and identifies differentially regulated isoforms or exons
    across samples."""

    homepage = "https://miso.readthedocs.io/en/fastmiso/"
    pypi = "misopy/misopy-0.5.4.tar.gz"

    version("0.5.4", sha256="377a28b0c254b1920ffdc2d89cf96c3a21cadf1cf148ee6d6ef7a88ada067dfc")

    depends_on("py-setuptools", type="build")
    depends_on("python@2.6:", type=("build", "run"))
    depends_on("py-numpy@1.5.0:", type=("build", "run"))
    depends_on("py-scipy@0.9.0:", type=("build", "run"))
    depends_on("py-pysam@0.6.0:", type=("build", "run"))
    depends_on("py-matplotlib", type=("build", "run"))
    depends_on("samtools")
    depends_on("bedtools2")