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diff --git a/var/spack/repos/builtin/packages/ants/package.py b/var/spack/repos/builtin/packages/ants/package.py
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+# Copyright 2013-2018 Lawrence Livermore National Security, LLC and other
+# Spack Project Developers. See the top-level COPYRIGHT file for details.
+#
+# SPDX-License-Identifier: (Apache-2.0 OR MIT)
+
+from spack import *
+
+
+class Ants(CMakePackage):
+    """ANTs extracts information from complex datasets that include imaging.
+       Paired with ANTsR (answer), ANTs is useful for managing, interpreting
+       and visualizing multidimensional data. ANTs is popularly considered a
+       state-of-the-art medical image registration and segmentation toolkit.
+       ANTs depends on the Insight ToolKit (ITK), a widely used medical image
+       processing library to which ANTs developers contribute.
+    """
+
+    homepage = "http://stnava.github.io/ANTs/"
+    url      = "https://github.com/ANTsX/ANTs/archive/v2.2.0.tar.gz"
+
+    version('2.2.0', '5661b949268100ac0f7baf6d2702b4dd')
+
+    def install(self, spec, prefix):
+        with working_dir(join_path('spack-build', 'ANTS-build'), create=False):
+            make("install")
+        install_tree('Scripts', prefix.bin)
+
+    def setup_environment(self, spack_env, run_env):
+        run_env.set('ANTSPATH', self.prefix.bin)