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diff --git a/var/spack/repos/builtin/packages/mapsplice2/package.py b/var/spack/repos/builtin/packages/mapsplice2/package.py
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+# Copyright 2013-2021 Lawrence Livermore National Security, LLC and other
+# Spack Project Developers. See the top-level COPYRIGHT file for details.
+#
+# SPDX-License-Identifier: (Apache-2.0 OR MIT)
+
+
+from spack import *
+
+
+class Mapsplice2(MakefilePackage):
+ """MapSplice is a software for mapping RNA-seq data to reference genome
+ for splice junction discovery that depends only on reference genome,
+ and not on any further annotations."""
+
+ homepage = "http://www.netlab.uky.edu/p/bioinfo/MapSplice2"
+ url = "https://protocols.netlab.uky.edu/~zeng/MapSplice-v2.2.1.zip"
+
+ version(
+ "2.2.1",
+ sha256="4f3c1cb49ba0abcfc952de5946ee0b56db28c51f4f4d4f5abca66b4461ca7d05",
+ )
+
+ patch("Makefile.patch")
+ patch("mapsplice_ebwt.patch")
+
+ depends_on("bowtie")
+ depends_on("ncurses", type="link")
+ depends_on("samtools", type="link")
+ depends_on("python", type="run")
+
+ def edit(self, spec, prefix):
+ for iscan in find(
+ "src",
+ [
+ "SamRec.*",
+ "AlignmentHandler.cpp",
+ "JunctionHandler.cpp",
+ "FusionSamRec.*",
+ ],
+ recursive=True,
+ ):
+ m = FileFilter(iscan)
+ m.filter(r"iscanonical", "iscanonical2")
+
+ for makefile in find(".", "[Mm]akefile", recursive=True):
+ m = FileFilter(makefile)
+ m.filter("g++", "{0}".format(spack_cxx), string=True)
+ m.filter(r"CC =.*", "CC = {0}".format(spack_cc))
+ m.filter(r"CPP =.*", "CPP = {0}".format(spack_cxx))
+ m.filter(r"CXX =.*", "CXX = {0}".format(spack_cxx))
+
+ def install(self, spec, prefix):
+ install("mapsplice.py", prefix)
+ install_tree("bin", prefix.bin)