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+# Copyright 2013-2018 Lawrence Livermore National Security, LLC and other
+# Spack Project Developers. See the top-level COPYRIGHT file for details.
+#
+# SPDX-License-Identifier: (Apache-2.0 OR MIT)
+
+from spack import *
+
+
+class RTmixclust(RPackage):
+ """Implementation of a clustering method for time series gene expression
+ data based on mixed-effects models with Gaussian variables and
+ non-parametric cubic splines estimation. The method can robustly account
+ for the high levels of noise present in typical gene expression time
+ series datasets."""
+
+ homepage = "https://bioconductor.org/packages/TMixClust/"
+ git = "https://git.bioconductor.org/packages/TMixClust.git"
+
+ version('1.0.1', commit='0ac800210e3eb9da911767a80fb5582ab33c0cad')
+
+ depends_on('r-gss', type=('build', 'run'))
+ depends_on('r-mvtnorm', type=('build', 'run'))
+ depends_on('r-zoo', type=('build', 'run'))
+ depends_on('r-cluster', type=('build', 'run'))
+ depends_on('r-biocparallel', type=('build', 'run'))
+ depends_on('r-flexclust', type=('build', 'run'))
+ depends_on('r-biobase', type=('build', 'run'))
+ depends_on('r-spem', type=('build', 'run'))
+ depends_on('r@3.4.3:3.4.9', when='@1.0.1')