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# Copyright 2013-2022 Lawrence Livermore National Security, LLC and other
# Spack Project Developers. See the top-level COPYRIGHT file for details.
#
# SPDX-License-Identifier: (Apache-2.0 OR MIT)
from spack import *
class RMulttest(RPackage):
"""Resampling-based multiple hypothesis testing.
Non-parametric bootstrap and permutation resampling-based multiple
testing procedures (including empirical Bayes methods) for controlling
the family-wise error rate (FWER), generalized family-wise error rate
(gFWER), tail probability of the proportion of false positives (TPPFP),
and false discovery rate (FDR). Several choices of bootstrap-based null
distribution are implemented (centered, centered and scaled, quantile-
transformed). Single-step and step-wise methods are available. Tests
based on a variety of t- and F-statistics (including t-statistics based
on regression parameters from linear and survival models as well as
those based on correlation parameters) are included. When probing
hypotheses with t-statistics, users may also select a potentially faster
null distribution which is multivariate normal with mean zero and
variance covariance matrix derived from the vector influence function.
Results are reported in terms of adjusted p-values, confidence regions
and test statistic cutoffs. The procedures are directly applicable to
identifying differentially expressed genes in DNA microarray
experiments."""
bioc = "multtest"
version('2.50.0', commit='1de96649a942b115d3d554394514745e86eb3fd3')
version('2.46.0', commit='c4dd27b333c80313a88668b59d0299988c6478a2')
version('2.40.0', commit='5f00017c2d3a31e05e1cfe06d9f7afdee19f8473')
version('2.38.0', commit='4dfe71cecfb298a94521088fb7bd83c5498d2915')
version('2.36.0', commit='babb15e8d110eb72300ad59cf7e53386237a4198')
version('2.34.0', commit='6ef873e05e6c93ede54f3421424f56eda057cd54')
version('2.32.0', commit='c5e890dfbffcc3a3f107303a24b6085614312f4a')
depends_on('r@2.10:', type=('build', 'run'))
depends_on('r-biocgenerics', type=('build', 'run'))
depends_on('r-biobase', type=('build', 'run'))
depends_on('r-survival', type=('build', 'run'))
depends_on('r-mass', type=('build', 'run'))
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